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Fig. 5 | Malaria Journal

Fig. 5

From: A non-lethal malarial infection results in reduced drug metabolizing enzyme expression and drug clearance in mice

Fig. 5

Effects of P. chabaudi infection on expression of cytokines and cytokine target genes in mouse livers. Mice were euthanized at 6, 8 and 12 days after infection with P. chabaudi and their livers analysed by RT-qPCR for mRNA expression of the analysed genes. The data are the average of two separate experiments. Values are mean ± SD, and expression in naive mice was set at 1. Differences in mRNA expression between control and infected mice among the groups were analysed by MANOVA with Bonferroni corrected one-way ANOVAs as a post hoc test. *P < 1.47e−03, **P < 7.35e−04, ***P < 1.47e−05, significantly different from naïve group. NT, not tested for significance. For days 6, 8 and 12, n = 4, 6 and 4 in the naïve groups and n = 8, 10 and 8 in the infected groups, respectively

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