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Table 2 Proportion of individuals (all ages and under 5 years) found to be malaria seropositive by species and by antigen in malaria endemic areas of Ethiopia, 2015

From: Multiplex serology demonstrate cumulative prevalence and spatial distribution of malaria in Ethiopia

Plasmodium species

Antigens

% seropositive (95% CI) (all ages)

% seropositive (95% CI) (under 5 years)

P. falciparum

MSP-1

23.8 (21.4–26.3)

12.3 (10.6–14.2)

AMA-1

24.5 (22.4–26.7)

11.3 (9.8–13.0)

Pf positive (MSP-1 and/or AMA-1)

32.1 (29.8–34.4)

18.0 (16.1–20.1)

P. vivax

MSP-1

21.2 (19.2–23.4)

12.3 (10.5–14.4)

AMA-1

14.4 (12.7–16.2)

6.7 (5.5–8.0)

Pv positive (MSP-1 and/or AMA-1)

25.0 (22.7–27.3)

14.8 (12.7–17.2)

P. malariaea

MSP-1

8.6 (7.6–9.7)

6.1 (5.0–7.3)

P. ovale a

MSP-1

3.1 (2.5–3.8)

2.0 (1.4–2.7)

Any Plasmodium

Pf (MSP-1/AMA-1) or Pv (MSP-1/AMA-1) or Pm MSP-1 or Po MSP-1

44.5 (41.9–47.2)

30.2 (27.3–33.2)

Either P. falciparum or P. vivax

Pf (MSP-1/AMA-1) or Pv (MSP-1/AMA-1)

41.1 (38.5–43.7)

26.7 (24.0–29.5)

Both P. falciparum and P. vivax

Pf (MSP-1/AMA-1) and Pv (MSP-1/AMA-1)

6.6 (5.5–8.0)

1.7 (1.2–2.4)

  1. Samples positive for Merozoite Surface Protein-1 (MSP-1) and/or Apical Membrane Antigen-1 (AMA-1) for the respective species were considered positive for that species
  2. Pf, Plasmodium falciparum; Pm, Plasmodium malariae; Po, Plasmodium ovale; Pv, Plasmodium vivax
  3. aNormal approach (mean seronegative +3sd) to defining cut-off level used for P. malariae and P. ovale