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Table 2 Proportion of individuals (all ages and under 5 years) found to be malaria seropositive by species and by antigen in malaria endemic areas of Ethiopia, 2015

From: Multiplex serology demonstrate cumulative prevalence and spatial distribution of malaria in Ethiopia

Plasmodium species Antigens % seropositive (95% CI) (all ages) % seropositive (95% CI) (under 5 years)
P. falciparum MSP-1 23.8 (21.4–26.3) 12.3 (10.6–14.2)
AMA-1 24.5 (22.4–26.7) 11.3 (9.8–13.0)
Pf positive (MSP-1 and/or AMA-1) 32.1 (29.8–34.4) 18.0 (16.1–20.1)
P. vivax MSP-1 21.2 (19.2–23.4) 12.3 (10.5–14.4)
AMA-1 14.4 (12.7–16.2) 6.7 (5.5–8.0)
Pv positive (MSP-1 and/or AMA-1) 25.0 (22.7–27.3) 14.8 (12.7–17.2)
P. malariaea MSP-1 8.6 (7.6–9.7) 6.1 (5.0–7.3)
P. ovale a MSP-1 3.1 (2.5–3.8) 2.0 (1.4–2.7)
Any Plasmodium Pf (MSP-1/AMA-1) or Pv (MSP-1/AMA-1) or Pm MSP-1 or Po MSP-1 44.5 (41.9–47.2) 30.2 (27.3–33.2)
Either P. falciparum or P. vivax Pf (MSP-1/AMA-1) or Pv (MSP-1/AMA-1) 41.1 (38.5–43.7) 26.7 (24.0–29.5)
Both P. falciparum and P. vivax Pf (MSP-1/AMA-1) and Pv (MSP-1/AMA-1) 6.6 (5.5–8.0) 1.7 (1.2–2.4)
  1. Samples positive for Merozoite Surface Protein-1 (MSP-1) and/or Apical Membrane Antigen-1 (AMA-1) for the respective species were considered positive for that species
  2. Pf, Plasmodium falciparum; Pm, Plasmodium malariae; Po, Plasmodium ovale; Pv, Plasmodium vivax
  3. aNormal approach (mean seronegative +3sd) to defining cut-off level used for P. malariae and P. ovale