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Table 1 Four-day chemosuppressive anti-malarial activity of 80% methanolic crude extract of the roots of Euphorbia abyssinica against Plasmodium berghei infection in mice

From: Anti-malarial activity of the root extract of Euphorbia abyssinica (Euphorbiaceae) against Plasmodium berghei infection in mice

Treatments

Doses

Parasitaemia (%)

Chemosuppression (%)

Distilled water

10 ml/kg

24.90 ± 1.54

0.00

Euphorbia abyssinica crude root extract

200 mg/kg

8.25 ± 0.56

66.87a1,c2,d1,e1

400 mg/kg

3.75 ± 0.75

84.94a1,b2,e3

600 mg/kg

1.57 ± 0.49

93.69a1,b1

Chloroquine

25 mg/kg

0.60 ± 0.38

97.59a1,b1,c3

  1. Values are expressed as mean ± SEM; n = 5
  2. 1P < 0.001; 2P < 0.01; 3P < 0.05
  3. aAs compared to negative control
  4. bAs compared to 200 mg/kg extract
  5. cAs compared to 400 mg/kg extract
  6. dAs compared to 600 mg/kg extract
  7. eAs compared to positive control
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Malaria Journal

ISSN: 1475-2875

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