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Table 2 Effect of 80% methanolic crude extract of the roots of Euphorbia abyssinica on the mean survival times of Plasmodium berghei infected mice

From: Anti-malarial activity of the root extract of Euphorbia abyssinica (Euphorbiaceae) against Plasmodium berghei infection in mice

Treatments

Doses

Mean survival times (days)

Distilled water

10 ml/kg

7.40 ± 0.51

Euphorbia abyssinica crude root extract

200 mg/kg

9.00 ± 0.71d2,e1

400 mg/kg

9.80 ± 0.80e1

600 mg/kg

12.00 ± 0.71a1,b2,e2

Chloroquine

25 mg/kg

15.00 ± 0.00a1,b1,c1,d2

  1. Values are expressed as mean ± SEM; n = 5
  2. 1P < 0.001; 2P < 0.05
  3. aAs compared to negative control
  4. bAs compared to 200 mg/kg extract
  5. cAs compared to 400 mg/kg extract
  6. dAs compared to 600 mg/kg extract
  7. eAs compared to positive control
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Malaria Journal

ISSN: 1475-2875

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