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Table 3 Effect of 80% methanolic crude extract of the roots of Euphorbia abyssinica on the body weights of Plasmodium berghei infected mice

From: Anti-malarial activity of the root extract of Euphorbia abyssinica (Euphorbiaceae) against Plasmodium berghei infection in mice

Treatments Doses Body weight (g)
D0-weight D4-weight Weight change
Distilled water 10 ml/kg 40.00 ± 2.64 36.34 ± 2.40 − 3.66
Euphorbia abyssinica crude root extract 200 mg/kg 37.72 ± 0.78 34.30 ± 1.70 − 3.42c1
400 mg/kg 43.76 ± 1.83 42.78 ± 1.87 − 0.98
600 mg/kg 41.92 ± 1.07 40.40 ± 1.17 − 1.52
Chloroquine 25 mg/kg 40.26 ± 0.80 41.38 ± 0.87 1.12a1,b1
  1. Values are expressed as mean ± SEM; n = 5
  2. 1P < 0.01
  3. aAs compared to negative control
  4. bAs compared to 200 mg/kg extract
  5. cAs compared to positive control