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Table 2 Contingency analysis for interruption of transmission with RCD stratified by case management levels

From: Modelling reactive case detection strategies for interrupting transmission of Plasmodium falciparum malaria

E14 (%)Transmission interruptedTotalEffectivenessPAF (%)ap-value
RCD+ (e1)RCD− (e0)RCD+(n1)RCD− (n0)
13.944218710,0004000.51 (0.41, 0.59)49.8 (39.7, 58.2)< 0.001
21.8 (REF)561813010,0004000.42 (0.33, 0.50)41.2 (32.4, 48.8)< 0.001
26.0602312110,0004000.50 (0.42, 0.57)48.8 (40.7, 55.8)< 0.001
36.7676015010,0004000.44 (0.37, 0.51)43.6 (36.1, 50.2)< 0.001
46.1758621810,0004000.28 (0.21, 0.34)27.4 (20.7, 33.5)< 0.001
54.6788322410,0004000.29 (0.22, 0.35)28.2 (21.8, 34.0)< 0.001
62.1851019110,0004000.44 (0.38, 0.49)42.9 (36.9, 48.4)< 0.001
68.9860424410,0004000.29 (0.23, 0.35)28.3 (22.6, 33.6)< 0.001
Total55,405136580,00032000.38 (0.36, 0.41)37.5 (35.0, 39.9)< 0.001
  1. The total number of simulation runs at each case management level is 11,400 with 11,000 RCD+ and 400 RCD−. E14 is the probability of effective treatment of any clinical case within 14 days. REF indicates the reference scenario
  2. aWald confidence limits
  3. †Chi-squared