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Fig. 2 | Malaria Journal

Fig. 2

From: Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag

Fig. 2

Seroprevalence of DBL-α tag fragments and parent DBL-CIDR head structures recognized at pre-season for each PfEMP1 in children and adults. Paediatric sera recognized a discordant proportion of the DBL-α tag and parent DBL-CIDR head structure for two PfEMP1s, PF3D7_0632500 and PF3D7_0317400. Adult sera recognized discordant proportions of DBL-α tag and parent DBL-CIDR head structure for three PfEMP1s, PF3D7_1100200, PF3D7_0632500, and PF3D7_0808700. (*P < 0.05, **P < 0.01; ***P < 0.001. The McNemar’s test was used to compare tags and head structures within paediatric and adults groups. For comparisons between adults and children, the Chi square test was used.) PfEMP1, Plasmodium falciparum erythrocyte membrane protein-1; DBL, Duffy binding-like; CIDR, cysteine-rich interdomain region

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Malaria Journal

ISSN: 1475-2875

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