Fig. 5From: Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use in Mpumalanga Province, South Africa (2001–2018)a Prevalence of dhfr triple, dhps double and SP quintuple mutations in Plasmodium falciparum isolates from Mpumalanga Province, South Africa, by year (2001–2018), b changes in the prevalence of pure wild dhps437A, mutant dhps437G and mixed dhpsA437G alleles (2001–2018) and c pure wild dhps540K, mutant dhps540E and mixed dhpsK540E alleles (2001–2018)Back to article page