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Table 1 Clinical characteristics of study participants according to HIV infection status

From: HIV infection drives IgM and IgG3 subclass bias in Plasmodium falciparum-specific and total immunoglobulin concentration in Western Kenya

 

HIV-negative

HIV-positive

p value

Number of participants (N)

52

138

 

Age, median (IQR)

24.6 (21.6, 32.2)

29.4 (25.3, 36.2)

< 0.001

Female sex, N (%)

25 (48.1)

84 (60.9)

0.11

Malaria Positive, N (%)

3 (5.8)

12 (8.6)

0.55

Bed net use, N (%)

43 (84.3)a

107 (84.3)b

0.99

CRP, g/dL, median (IQR)

0.52 (0.27, 1.15)

4.72 (0.867, 26.12)

< 0.0001

CD4, cells/mL, median (IQR)

–

301 (180, 476)c

–

CD4 < 200, N (%)

–

42 (30.7)

–

HIV-1 Viral load, copies/mL, median (IQR)

–

50,370 (14,546–198,155)c

–

  1. p-value comparing HIV-negative vs. HIV-positive participants from Chi square for proportions (female sex, malaria positive, CD4+ counts < 200), and Mann–Whitney test for medians (CRP concentrations and age)
  2. Statistically significant differences (p < 0.05) are displayed in italics
  3. IQR interquartile range: 25th percentile–75th percentile
  4. aN = 51
  5. bN = 136
  6. cN = 137