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Table 2 Proportion of study participants with a reactive IgG, IgM or IgG subclass antibodies to P. falciparum antigens AMA-1 and GLURP-R0, according to HIV infection status

From: HIV infection drives IgM and IgG3 subclass bias in Plasmodium falciparum-specific and total immunoglobulin concentration in Western Kenya

Recombinant malaria antigens HIV negative (N = 52) HIV positive (N = 129) p valuea
IgM-AMA1, n (%) 7 (13) 65 (50) < 0.001
IgM-GLURP-R0, n (%) 21 (40) 94 (73) < 0.001
IgG-AMA1, n (%) 41 (79) 115 (89) 0.07
IgG-GLURP-R0, n (%) 24 (46) 71 (55) 0.28
IgG1-AMA1, n (%) 31 (60) 117 (91) < 0.001
IgG1-GLURP-R0, n (%) 14 (27) 90 (70) < 0.001
IgG2-AMA1, n (%) 6 (12) 24 (19) 0.25
IgG2-GLURP-R0, n (%) 12 (23) 30 (23) 0.98
IgG3-AMA1, n (%) 28 (54) 114 (88) < 0.001
IgG3-GLURP-R0, n (%) 42 (81) 124 (96) 0.001
IgG4-AMA1, n (%) 27 (52) 63 (49) 0.71
IgG4-GLURP-R0, n (%) 1 (2) 2 (2) 0.86
  1. Statistically significant differences (p < 0.05) are displayed in italics
  2. aχ2 test