TY - JOUR AU - Negri, Agata AU - Ferrari, Marco AU - Nodari, Riccardo AU - Coppa, Edoardo AU - Mastrantonio, Valentina AU - Zanzani, Sergio AU - Porretta, Daniele AU - Bandi, Claudio AU - Urbanelli, Sandra AU - Epis, Sara PY - 2019 DA - 2019/08/28 TI - Gene silencing through RNAi and antisense Vivo-Morpholino increases the efficacy of pyrethroids on larvae of Anopheles stephensi JO - Malaria Journal SP - 294 VL - 18 IS - 1 AB - Insecticides are still at the core of insect pest and vector control programmes. Several lines of evidence indicate that ABC transporters are involved in detoxification processes against insecticides, including permethrin and other pyrethroids. In particular, the ABCG4 gene, a member of the G subfamily, has consistently been shown to be up-regulated in response to insecticide treatments in the mosquito malaria vector Anopheles stephensi (both adults and larvae). SN - 1475-2875 UR - https://doi.org/10.1186/s12936-019-2925-5 DO - 10.1186/s12936-019-2925-5 ID - Negri2019 ER -