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Table 3 Performance of the highly sensitive rapid diagnostic test by malaria prevalence

From: Field performance of the malaria highly sensitive rapid diagnostic test in a setting of varying malaria transmission

 

Very low transmission (prevalence < 5%)

Low-moderate transmission (prevalence 5 to < 20%)

High transmission (prevalence 20–50%)

HS-RDT

HS-RDT

HS-RDT

Positive

Negative

Total

Positive

Negative

Total

Positive

Negative

Total

PCR positive

14

18

32

92

206

298

85

82

167

PCR negative

77

777

854

230

1916

2146

72

229

301

 Total

91

795

886

322

2122

2444

157

311

468

PCR prevalence

3.6 (2.5–5.1)

12.2 (10.9–13.5)

35.7 (31.3–40.2)

Sensitivity (95% CI)

43.8 (26.4–62.3)

30.9 (25.6–36.1)

50.9 (43.3–58.5)

Specificity (95% CI)

90.9 (89.1–92.9)

89.3 (87.9–90.6)

76.1 (71.3–80.9)

Positive predictive value (95% CI)

15.4 (8.7–24.5)

28.6 (23.6–33.5)

54.1 (46.4–61.9)

Negative predictive value (95% CI)

97.7 (96.4–98.7)

90.3 (89.0–91.6)

73.6 (68.7–78.5)