Fipronil and ivermectin treatment of cattle reduced the survival and ovarian development of field-collected Anopheles albimanus in a pilot trial conducted in northern Belize

Malaria Journal

Table 4 Best-fit generalized linear mixed effects model (binomial) of variables and interactions that influenced ovary development

Fixed effects	Groups	Estimate	SE	p value	Odds ratio (95% CI)
Intercept		1.315	0.369	< 0.0004	3.724 (3.000, 4.448)
Treatment	Control (n = 196)	–	–	–	–
	Fipronil (n = 185)	− 3.379	0.407	< 0.0001	0.0314 (− 0.764, 0.832)
	Ivermectin (n = 91)	− 1.776	0.455	0.0001	0.169 (− 0.722, 1.061)
Day after treatment		0.060	0.033	0.07	1.062 (0.998, 1.126)

Model: FullyGravid ~ Treatment + DayAfterTreat + (1|CowID), where the fixed effects were ‘Treatment’ (n = total number of mosquitoes dissected per treatment group) and ‘Day After Treatment’. The random effect was ‘CowID’ (i.e., the six individual heifers. Standard deviation = 0.250)