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Fig. 3 | Malaria Journal

Fig. 3

From: Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates

Fig. 3

Parasite line competitive growth assays suggest a fitness advantage in the NHP4026 line. NHP4026, a slow clearance kelch13-wt isolate, was able to fully outcompete all seven isolates it was matched with in pairwise competitions, suggesting a potential fitness advantage. In NHP4026 versus NF54 (kelch13-wt, fast clearance), NF54 initially held a greater ratio of parasitaemia, but NHP4026 overcame NF54 around day 30 and fully outcompeted NF54 by day 60 (n = 3; a). NHP4026 outcompeted NHP4076 (kelch13 E252Q, slow clearance) by day 24 (n = 3; b), and outcompeted NHP4333 (kelch13 G538V, slow-clearance) by day 40 (n = 3; c)

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