Table 2 Estimates of DNA sequence polymorphism and tests of neutrality at PfAMA-1 among other global plasmodium falciparum isolates
Isolate | S | Total no. of mutations | K | H | Hd ± SD | π ± SD | Tajima’s D | Fu and Li’s D | Fu and Li’s F |
|---|---|---|---|---|---|---|---|---|---|
Bioko Island (n = 214) | 56 | 64 | 12.795 | 131 | 0.9911 ± 0.0017 | 0.02776 ± 0.00042 | 0.56734 (P > 0.10) | − 0.27228 (P > 0.10) | 0.12925 (P > 0.10) |
Ghana (n = 37) | 37 | 41 | 12.555 | 22 | 0.967 ± 0.012 | 0.02717 ± 0.00090 | 1.01706 (P > 0.10) | 1.29910 (P > 0.10) | 1.42603 (P > 0.10) |
Tanzania (n = 62) | 40 | 45 | 12.460 | 35 | 0.972 ± 0.008 | 0.02697 ± 0.00061 | 1.01442 (P > 0.10) | 1.59904 (P < 0.05) | 1.64786 (0.10 > P > 0.05) |
Nigeria (n = 51) | 38 | 42 | 12.409 | 35 | 0.979 ± 0.008 | 0.02686 ± 0.00068 | 1.13803 (P > 0.10) | 1.53256 (P < 0.05) | 1.65608 (0.10 > P > 0.05) |
Solomon (n = 50) | 31 | 32 | 11.791 | 9 | 0.844 ± 0.021 | 0.02552 ± 0.00074 | 2.19486 (P < 0.05) | 1.34414 (0.10 > P>0.05) | 1.96178 (P < 0.02) |
Gambia (n = 114) | 42 | 48 | 12.267 | 51 | 0.970 ± 0.006 | 0.02655 ± 0.00051 | 1.12103 (P > 0.10) | 1.22880 (P > 0.10) | 1.42163 (P > 0.10) |
Kenya (n = 129) | 42 | 48 | 12.886 | 64 | 0.980 ± 0.004 | 0.02789 ± 0.00038 | 1.42081 (P > 0.10) | 1.71986 (P < 0.02) | 1.91516 (P < 0.05) |
Benin (n = 23) | 34 | 37 | 11.605 | 22 | 0.993 ± 0.014 | 0.02577 ± 0.00237 | 0.65437 (P > 0.10) | 1.22364 (P > 0.10) | 1.22668 (P > 0.10) |
Venezuela (n = 30) | 15 | 15 | 5.617 | 6 | 0.482 ± 0.101 | 0.01216 ± 0.00228 | 1.65975 (P > 0.10) | 1.14686 (P > 0.10) | 1.53677 (0.10 > P > 0.05) |
Thailand (n = 80) | 32 | 34 | 11.428 | 19 | 0.919 ± 0.012 | 0.02474 ± 0.00067 | 2.11203 (P < 0.05) | 0.83255 (P > 0.10) | 1.58398 (0.10 > P > 0.05) |