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Table 2 Gene ontology (GO) term annotation of genes preferentially expressed in (i) EEF stages and (ii) asexual EF stages

From: Transcriptome analysis of Plasmodium berghei during exo-erythrocytic development

Biological process ID

Process description

Annotated

Observed

P value

(i) Preferentially expressed in exo-erythrocytic stage (24 h, 48 h, 54 h and 60 h)

 GO:0006633

Fatty acid biosynthetic process

9

6

4e−06

 GO:0044409

Entry into host

33

7

0.0036

 GO:0006272

Leading strand elongation

2

2

0.0040

 GO:0033014

Tetrapyrrole biosynthetic process

9

4

0.0042

 GO:0006260

DNA replication

39

10

0.0110

 GO:0055114

Oxidation–reduction process

83

12

0.0215

 GO:0006270

DNA replication initiation

4

2

0.0219

 GO:0006334

Nucleosome assembly

4

2

0.0219

(ii) Preferentially expressed in erythrocytic stage (ring 4 h, trophozoite 16 h)

 GO:0006928

Movement of cell or subcellular component

34

6

0.00036

 GO:0044053

Translocation of peptides or proteins into host cell cytoplasm

3

2

0.00256

 GO:0040011

Locomotion

22

5

0.00644

 GO:0035891

Exit from host cell

8

2

0.02169

 GO:0009405

Pathogenesis

8

2

0.02169

 GO:0030833

Regulation of actin filament polymerization

1

1

0.02978

 GO:0006166

Purine ribonucleoside salvage

1

1

0.02978

 GO:0019510

S-Adenosylhomocysteine catabolic process

1

1

0.02978

 GO:0010323

Negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway

1

1

0.02978

 GO:0020035

Cytoadherence to microvasculature, mediated by symbiont protein

1

1

0.02978

 GO:0007050

Cell cycle arrest

1

1

0.02978

  1. The number of annotated genes (number genes per GO term present in the entire RNA-seq study) and observed genes (number of genes per GO term preferentially expressed in…) per Biological Process are listed. Only GO terms with P-values < 0.05 are shown