Table 3 Gene ontology (GO) term annotation of genes preferentially expressed in (i) EEF merozoites and (ii) EF merozoites
From: Transcriptome analysis of Plasmodium berghei during exo-erythrocytic development
Biological process ID | Process description | Annotated | Observed | P value |
|---|---|---|---|---|
(i) Preferentially expressed in exo-erythrocytic stage merozoites (DCs/merosomes) | ||||
GO:0010467 | Gene expression | 462 | 181 | 3.0e−22 |
GO:0042254 | Ribosome biogenesis | 63 | 47 | 4.6e−20 |
GO:0043604 | Amide biosynthetic process | 219 | 98 | 1.1e−17 |
GO:0032774 | RNA biosynthetic process | 103 | 35 | 0.00017 |
GO:0017183 | Peptidyl-diphthamide biosynthetic process from peptidyl-histidine | 5 | 4 | 0.00700 |
GO:0000398 | mRNA splicing, via spliceosome | 43 | 15 | 0.01718 |
GO:0008295 | Spermidine biosynthetic process | 2 | 2 | 0.04105 |
GO:0008612 | Peptidyl-lysine modification to peptidyl-hypusine | 2 | 2 | 0.04105 |
(ii) Preferentially expressed in erythrocytic stage merozoites (22 h schizonts) | ||||
GO:0007264 | Small gtpase mediated signal transduction | 26 | 14 | 0.0014 |
GO:0006260 | DNA replication | 39 | 20 | 0.0049 |
GO:0045184 | Establishment of protein localization | 93 | 34 | 0.0060 |
GO:0007017 | Microtubule-based process | 35 | 15 | 0.0075 |
GO:0000041 | Transition metal ion transport | 7 | 6 | 0.0151 |
GO:0006465 | Signal peptide processing | 5 | 4 | 0.0153 |
GO:0006848 | Pyruvate transport | 3 | 3 | 0.0154 |
GO:0006497 | Protein lipidation | 21 | 10 | 0.0196 |
GO:0006511 | Ubiquitin-dependent protein catabolic process | 38 | 16 | 0.0248 |
GO:0043248 | Proteasome assembly | 8 | 5 | 0.0267 |
GO:0006310 | DNA recombination | 9 | 6 | 0.0366 |
GO:0006468 | Protein phosphorylation | 82 | 28 | 0.0437 |