Fig. 1

A schematic representation of the pfcsp gene showing the N-terminal region described in this study; DGNNEDNEKLRKPKHKKLKQPADGNPDP (underlined KLKQP motif responsible for the sporozoite entry into hepatocytes). In the central repeat region NANP (N, asparagine; A, alanine and P, proline) and NVDP (N, asparagine; V, valine; D, aspartic acid and P, proline) repeats. C-terminal region contains Th2R and Th3R epitopes