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Fig. 3 | Malaria Journal

Fig. 3

From: Enhanced uptake, high selective and microtubule disrupting activity of carbohydrate fused pyrano-pyranones derived from natural coumarins attributes to its anti-malarial potential

Fig. 3

Effect of carbohybrid 12 on progression through asexual blood stages of P. falciparum. a Timeline representing different time points in the blood stage developmental cycle of P. falciparum (black line). # Sc1, # Sc2 and # Sc3 represent different time points of treatment with carbohybrid 12 at rings, trophozoites and schizonts respectively. The bar graph shows percent growth inhibition upon carbohybrid 12 treatment with respect to (w.r.t.) control. b P. falciparum 3D7 cultures were treated with carbohybrid 12 (C-12) at 8 µM or 15 µM at rings (upper panel, # Sc1), trophozoites (bottom left, # Sc2) or schizonts (bottom right, # Sc3). Morphology of P. falciparum was observed by Giemsa stained smears at different timelines of progression through blood stages in each set as shown. The bar graph in each column represents percent parasitaemia w.r.t. untreated control

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