Skip to main content

Table 2 Summary of findings from the reviewed articles on P. falciparum pfhrp2 gene deletion

From: Systematic review of the status of pfhrp2 and pfhrp3 gene deletion, approaches and methods used for its estimation and reporting in Plasmodium falciparum populations in Africa: review of published studies 2010–2019

Country

First author

Areas of assessment

Reported level of pfhrp2 deletion (%)

Design and participants

Size of studies (no. of samples)

pfhrp2 and pfhrp3 double or pfhrp2 single deletion

Flanking genes

Lab methods

Mali [9]

Koita

Cross-sectional, Asymptomatic individuals

480

Only pfhrp2 deletion reported

Not reported

MSP2 PCR not reported

2

Kenya [16, 18]

Beshir

Cross-sectional, asymptomatic

131

Both pfhrp2 and pfhrp3 reported

Not reported

All methods reported

10a

Nderu

Cross-sectional, symptomatic individuals

400

Both pfhrp2 and pfhrp3 reported

Not reported

Details not accessed for review

0

DRC [15]

Parr

Cross-sectional, Asymptomatic individuals

2752

Both pfhrp2 and pfhrp3 reported

Not reported

MSP1 and MSP2 PCR not reported

6.4

Eritrea [10, 11]

Berhane

Cross-sectional, Symptomatic individuals

50

Both pfhrp2 and pfhrp3 reported

Reported

All Lab methods reported

62

Menegon

Cross-sectional

144

Both pfhrp2 and pfhrp3 reported

Not reported

Not available for review

9.7

Rwanda [8]

Kozycki

Cross-sectional, Symptomatic individuals

3291

Only pfhrp2 reported

Not reported

MSP1 and MSP2 PCR not reported

23a

Mozambique [12]

Gupta

Cross-sectional, Symptomatic individuals

1162

pfhrp2 and pfhrp3 reported

Not reported

MSP1 and MSP2 PCR not reported

1.45a

Senegal [14]

Wurtz

Cross-sectional, Symptomatic individuals

112

pfhrp2 and pfhrp3 reported

Not reported

MSP1 and MSP2 PCR not reported

2.4

Ghana [17]

Amoah

Cross-sectional, asymptomatic individuals

94

Only pfhrp2 reported

Not reported

MSP1 and MSP2 PCR not reported

36.2

Nigeria [13]

Funwei

Prospective cohort

309

pfhrp2 and pfhrp3 reported

Not reported

All Lab methods reported

17a

Zambia [19]

Kobayashi

Cross-sectional, asymptomatic

28

pfhrp2 and pfhrp3 reported

Not reported

MSP1, MSP2 not reported

10.7a

Angola [20]

Plucinski

Cross-sectional, asymptomatic

466

pfhrp2 and pfhrp3 reported

Not reported

MSP1, MSP2 not reported

0.4

Ethiopia [21]

Girma

Cross-sectional, asymptomatic

562

Only pfhrp2 reported

Not reported

Not available for review

4.8a

  1. apfhrp2 gene deletion estimate was based on a smaller denominator rather than total P. falciparum infected samples