Country | First author | Areas of assessment | Reported level of pfhrp2 deletion (%) | ||||
---|---|---|---|---|---|---|---|
Design and participants | Size of studies (no. of samples) | pfhrp2 and pfhrp3 double or pfhrp2 single deletion | Flanking genes | Lab methods | |||
Mali [9] | Koita | Cross-sectional, Asymptomatic individuals | 480 | Only pfhrp2 deletion reported | Not reported | MSP2 PCR not reported | 2 |
Beshir | Cross-sectional, asymptomatic | 131 | Both pfhrp2 and pfhrp3 reported | Not reported | All methods reported | 10a | |
Nderu | Cross-sectional, symptomatic individuals | 400 | Both pfhrp2 and pfhrp3 reported | Not reported | Details not accessed for review | 0 | |
DRC [15] | Parr | Cross-sectional, Asymptomatic individuals | 2752 | Both pfhrp2 and pfhrp3 reported | Not reported | MSP1 and MSP2 PCR not reported | 6.4 |
Berhane | Cross-sectional, Symptomatic individuals | 50 | Both pfhrp2 and pfhrp3 reported | Reported | All Lab methods reported | 62 | |
Menegon | Cross-sectional | 144 | Both pfhrp2 and pfhrp3 reported | Not reported | Not available for review | 9.7 | |
Rwanda [8] | Kozycki | Cross-sectional, Symptomatic individuals | 3291 | Only pfhrp2 reported | Not reported | MSP1 and MSP2 PCR not reported | 23a |
Mozambique [12] | Gupta | Cross-sectional, Symptomatic individuals | 1162 | pfhrp2 and pfhrp3 reported | Not reported | MSP1 and MSP2 PCR not reported | 1.45a |
Senegal [14] | Wurtz | Cross-sectional, Symptomatic individuals | 112 | pfhrp2 and pfhrp3 reported | Not reported | MSP1 and MSP2 PCR not reported | 2.4 |
Ghana [17] | Amoah | Cross-sectional, asymptomatic individuals | 94 | Only pfhrp2 reported | Not reported | MSP1 and MSP2 PCR not reported | 36.2 |
Nigeria [13] | Funwei | Prospective cohort | 309 | pfhrp2 and pfhrp3 reported | Not reported | All Lab methods reported | 17a |
Zambia [19] | Kobayashi | Cross-sectional, asymptomatic | 28 | pfhrp2 and pfhrp3 reported | Not reported | MSP1, MSP2 not reported | 10.7a |
Angola [20] | Plucinski | Cross-sectional, asymptomatic | 466 | pfhrp2 and pfhrp3 reported | Not reported | MSP1, MSP2 not reported | 0.4 |
Ethiopia [21] | Girma | Cross-sectional, asymptomatic | 562 | Only pfhrp2 reported | Not reported | Not available for review | 4.8a |