Table 3 Distribution of msp1 and msp2 allelic types of P. falciparum among different parasite densities in the China–Myanmar border region
Allelic type | Parasite density (no. of parasites/µl of blood) | Total | |||||
|---|---|---|---|---|---|---|---|
< 500 | 500–1000 | 1000–2500 | 2500–10,000 | 10,000–100,000 | ≥100,000 | n (%) | |
n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | ||
n = 11 | n = 22 | n = 44 | n = 66 | n = 61 | n = 11 | n = 215 | |
msp1 | |||||||
K1 | 4 (36.36) | 9 (40.91) | 18 (40.91) | 18 (27.27) | 14 (22.95) | 2 (18.18) | 65 (30.23) |
MAD20 | 5 (45.45) | 8 (36.36) | 17 (38.64) | 29 (43.94) | 22 (36.07) | 3 (27.27) | 84 (39.07) |
RO33 | 0 (0) | 0 (0) | 2 (4.55) | 3 (4.55) | 8 (13.11) | 6 (54.55) | 19 (8.84) |
K1/MAD20 | 2 (18.18) | 5 (22.73) | 2 (4.55) | 9 (13.64) | 7 (11.48) | 0 (0) | 25 (11.63) |
KI/RO33 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 2 (3.28) | 0 (0) | 2 (0.93) |
MAD20/RO33 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 2 (3.28) | 0 (0) | 2 (0.93) |
K1/MAD20/RO33 | 0 (0) | 0 (0) | 0 (0) | 3 (4.55) | 1 (1.64) | 0 (0) | 4 (1.86) |
Negative | 0 (0) | 0 (0) | 5 (11.36) | 4 (6.06) | 5 (8.2) | 0 (0) | 14 (6.51) |
Multiclonal isolates | 2 (18.18) | 5 (22.73) | 2 (4.55) | 12 (18.18) | 12 (19.67) | 0 (0) | 33 (15.35) |
Mean MOI | 1.32 ± 0.68 | 1.52 ± 0.73 | 1.67 ± 0.68 | 1.91 ± 0.86 | 1.80 ± 0.95 | 2.02 ± 0.83 | 1.76 ± 0.85 |
msp2 | |||||||
FC27 | 0 (0) | 1 (4.55) | 5 (11.36) | 17 (25.76) | 16 (26.23) | 2 (18.18) | 41 (19.07) |
3D7 | 1 (9.09) | 5 (22.73) | 10 (22.73) | 6 (9.09) | 3 (4.92) | 5 (45.45) | 30 (13.95) |
FC27/3D7 | 10 (90.91) | 15 (68.18) | 26 (59.09) | 41 (62.12) | 38 (62.3) | 3 (27.27) | 133 (61.86) |
Negative | 0 (0) | 1 (4.55) | 3 (6.82) | 2 (3.03) | 4 (6.56) | 1 (9.09) | 11 (5.12) |
Multiclonal isolates | 10 (90.91) | 15 (68.18) | 26 (59.09) | 41 (62.12) | 38 (62.3) | 3 (27.27) | 133 (61.86) |
Mean MOI | 1.32 ± 0.68 | 1.52 ± 0.73 | 1.67 ± 0.68 | 1.89 ± 0.86 | 1.80 ± 0.95 | 2.02 ± 0.83 | 2.21 ± 1.29 |