Skip to main content
Fig. 5 | Malaria Journal

Fig. 5

From: The persistence of naturally acquired antibodies and memory B cells specific to rhoptry proteins of Plasmodium vivax in patients from areas of low malaria transmission

Fig. 5

Rhoptry-specific MBCs detected 18 months post-infection. a The number of specific MBC responses to the PvRALP1-Ecto and PvRhopH2 antigens, and tetanus toxoid (TT) in PBMCs from subjects 18 months after P. vivax infection were determined by ELISPOT (n = 10). The frequency of MBCs was expressed per million cultured PBMCs. Each symbol represents the MBC number for one individual. The line reflects the median value. b The correlation analysis between the responses of rhoptry-specific MBCs and antibody in 10 subjects at 18 months post-infection. c The comparative analysis of anti-IgG1, -IgG2, -IgG3 and -IgG4 specific to PvRALP1-Ecto and PvRhopH2 proteins in 10 subjects at 18 months post-infection. The Kruskal–Wallis one-way ANOVA test was performed to compare the mean antibody levels of the difference IgG subclasses. The horizontal line represents mean values ± SEM. Dashed line indicates the cut-off value (RI ≥ 1)

Back to article page