TY - JOUR AU - Adegbite, Bayode R. AU - Edoa, Jean R. AU - Honkpehedji, Yabo J. AU - Zinsou, Frejus J. AU - Dejon-Agobe, Jean C. AU - Mbong-Ngwese, Mirabeau AU - Lotola-Mougueni, Fabrice AU - Koehne, Erik AU - Lalremruata, Albert AU - Kreidenweiss, Andrea AU - Nguyen, The T. AU - Kun, Jutta AU - Agnandji, Selidji T. AU - Lell, Bertrand AU - Safiou, Abdou R. AU - Obone Atome, Fridia A. AU - Mombo-Ngoma, Ghyslain AU - Ramharter, Michael AU - Velavan, Thirumalaisamy P. AU - Mordmüller, Benjamin AU - Kremsner, Peter G. AU - Adegnika, Ayola A. PY - 2019 DA - 2019/12/16 TI - Monitoring of efficacy, tolerability and safety of artemether–lumefantrine and artesunate–amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Lambaréné, Gabon: an open-label clinical trial JO - Malaria Journal SP - 424 VL - 18 IS - 1 AB - Malaria remains a major public health problem, affecting mainly low-and middle-income countries. The management of this parasitic disease is challenged by ever increasing drug resistance. This study, investigated the therapeutic efficacy, tolerability and safety of artemether–lumefantrine (AL) and artesunate–amodiaquine (AS–AQ), used as first-line drugs to treat uncomplicated malaria in Lambaréné, Gabon. SN - 1475-2875 UR - https://doi.org/10.1186/s12936-019-3015-4 DO - 10.1186/s12936-019-3015-4 ID - Adegbite2019 ER -