Analyte | IgG to AMA-1 | IgG to MSP-1 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Univariable | Multivariable & interaction with year | Univariable | Multivariable & interaction with year | |||||||
Coefficient (CI) | p-value | Coefficient (CI) | p-value | p-value Int | Coefficient (CI) | p-value | Coefficient (CI) | p-value | p-value Int | |
FGF | − 0.024 (− 0.048, 0) | 0.047 | − 0.068 (− 0.261, 0.125) | 0.486 | 0.636 | − 0.019 (− 0.036, − 0.002) | 0.027 | − 0.016 (− 0.162, 0.13) | 0.829 | 0.996 |
IL-1β | − 0.026 (− 0.054, 0.002) | 0.07 | − 0.046 (− 0.235, 0.144) | 0.636 | 0.658 | − 0.02 (− 0.037, − 0.003) | 0.022 | 0.004 (− 0.124, 0.132) | 0.956 | 0.954 |
G-CSF | − 0.002 (− 0.009, 0.004) | 0.419 | − 0.046 (− 0.091, 0) | 0.05 | 0.058 | − 0.002 (− 0.006, 0.002) | 0.359 | − 0.026 (− 0.062, 0.009) | 0.146 | 0.155 |
IL-10 | − 0.009 (− 0.035, 0.017) | 0.511 | − 0.098 (− 0.29, 0.094) | 0.315 | 0.331 | 0.001 (− 0.017, 0.02) | 0.886 | − 0.122 (− 0.272, 0.029) | 0.112 | 0.086 |
IL-13 | − 0.017 (− 0.02, − 0.007) | 0.001* | − 0.029 (− 0.108, 0.05) | 0.473 | 0.75 | − 0.012 (− 0.019, − 0.004) | 0.002* | 0.002 (− 0.06, 0.063) | 0.954 | 0.707 |
IL-6 | − 0.024 (− 0.071, 0.024) | 0.335 | 0.014 (− 0.235, 0.262) | 0.914 | 0.984 | − 0.033 (− 0.067, 0.001) | 0.055 | − 0.015 (− 0.22, 0.19) | 0.888 | 0.837 |
IL-12 | − 0.007 (− 0.012, − 0.002) | 0.004* | − 0.045 (− 0.083, − 0.008) | 0.018 | 0.042 | − 0.003 (− 0.007, 0) | 0.06 | − 0.01 (− 0.041, 0.021) | 0.531 | 0.639 |
RANTES | 0.005 (0.001, 0.01) | 0.014 | 0.015 (− 0.016, 0.047) | 0.338 | 0.501 | 0.002 (− 0.001, 0.005) | 0.124 | − 0.004 (− 0.029, 0.021) | 0.769 | 0.689 |
Eotaxin | − 0.011 (− 0.026, 0.004) | 0.141 | − 0.103 (− 0.216, 0.01) | 0.075 | 0.106 | − 0.005 (− 0.015, 0.006) | 0.385 | − 0.037 (− 0.126, 0.052) | 0.414 | 0.458 |
IL-17 | − 0.019 (− 0.058, 0.02) | 0.331 | 0.043 (− 0.258, 0.344) | 0.778 | 0.687 | 0.004 (− 0.024, 0.033) | 0.778 | − 0.135 (− 0.37, 0.099) | 0.256 | 0.229 |
MIP-1α | 0.005 (− 0.014, 0.025) | 0.591 | − 0.027 (− 0.13, 0.076) | 0.611 | 0.427 | − 0.008 (− 0.021, 0.006) | 0.269 | − 0.058 (− 0.141, 0.024) | 0.166 | 0.122 |
GM-CSF | − 0.021 (− 0.083, 0.041) | 0.5 | − 0.616 (− 1.092, − 0.141) | 0.011 | 0.013 | − 0.017 (− 0.062, 0.028) | 0.451 | − 0.336 (− 0.747, 0.075) | 0.109 | 0.113 |
MIP-1β | − 0.003 (− 0.021, 0.015) | 0.76 | − 0.03 (− 0.111, 0.051) | 0.463 | 0.365 | − 0.013 (− 0.026, − 0.001) | 0.039 | − 0.027 (− 0.092, 0.037) | 0.409 | 0.385 |
MCP-1 | − 0.00 (− 0.01, 0.005) | 0.504 | − 0.061 (− 0.11, − 0.012) | 0.015 | 0.014 | − 0.007 (− 0.012, − 0.001) | 0.017 | − 0.062 (− 0.1, − 0.024) | 0.001* | 0.002* |
IL-15 | − 0.004 (− 0.018, 0.011) | 0.626 | 0.064 (− 0.051, 0.18) | 0.272 | 0.245 | 0.003 (− 0.007, 0.013) | 0.531 | 0.033 (− 0.058, 0.125) | 0.475 | 0.518 |
EGF | − 0.01 (− 0.027, 0.008) | 0.27 | − 0.009 (− 0.141, 0.123) | 0.889 | 0.959 | − 0.006 (− 0.017, 0.005) | 0.289 | 0.008 (− 0.087, 0.103) | 0.871 | 0.852 |
IL-5 | − 0.036 (− 0.081, 0.009) | 0.121 | − 0.11 (− 0.46, 0.241) | 0.539 | 0.685 | − 0.008 (− 0.041, 0.024) | 0.613 | − 0.285 (− 0.557, − 0.013) | 0.04 | 0.048 |
HGF | − 0.005 (− 0.013, 0.002) | 0.16 | − 0.045 (− 0.099, 0.009) | 0.101 | 0.129 | − 0.001 (− 0.006, 0.004) | 0.632 | − 0.025 (− 0.067, 0.017) | 0.237 | 0.212 |
VEGF | − 0.027 (− 0.049, − 0.005) | 0.018 | 0.242 (0.111, 0.373) | <0.001* | <0.001* | − 0.022 (− 0.037, − 0.006) | 0.006* | 0.096 (− 0.011, 0.203) | 0.078 | 0.055 |
IFN-γ | 0.002 (− 0.009, 0.013) | 0.747 | − 0.014 (− 0.098, 0.069) | 0.735 | 0.7 | 0.004 (− 0.004, 0.012) | 0.31 | − 0.033 (− 0.1, 0.034) | 0.33 | 0.272 |
IFN-α | − 0.005 (− 0.012, 0.002) | 0.194 | − 0.09 (− 0.139, − 0.04) | <0.001* | 0.001* | − 0.005 (− 0.009, 0) | 0.067 | − 0.068 (− 0.106, − 0.03) | 0.001* | 0.001* |
IL-1RA | − 0.01 (− 0.018, − 0.003) | 0.007* | 0.025 (− 0.018, 0.068) | 0.261 | 0.145 | − 0.008 (− 0.013, − 0.002) | 0.004* | 0.034 (− 0.001, 0.07) | 0.055 | 0.036 |
TNF | 0.001 (− 0.029, 0.03) | 0.953 | − 0.056 (− 0.264, 0.151) | 0.592 | 0.527 | − 0.013 (− 0.034, 0.009) | 0.242 | − 0.089 (− 0.255, 0.077) | 0.292 | 0.287 |
IL-2 | 0.006 (− 0.03, 0.042) | 0.736 | − 0.006 (− 0.29, 0.279) | 0.968 | 0.936 | 0.018 (− 0.008, 0.043) | 0.178 | 0.005 (− 0.221, 0.23) | 0.969 | 0.907 |
IL-7 | − 0.009 (− 0.024, 0.006) | 0.249 | − 0.027 (− 0.155, 0.102) | 0.68 | 0.781 | − 0.002 (− 0.014, 0.009) | 0.678 | 0.082 (− 0.023, 0.186) | 0.126 | 0.114 |
IP-10 | − 0.037 (− 0.054, − 0.021) | <0.001* | − 0.087 (− 0.205, 0.032) | 0.152 | 0.377 | − 0.02 (− 0.031, − 0.008) | 0.001* | − 0.07 (− 0.163, 0.024) | 0.146 | 0.248 |
IL-2R | − 0.016 (− 0.024, − 0.009) | <0.001* | − 0.019 − 0.079, 0.04) | 0.52 | 0.909 | − 0.008 (− 0.013, − 0.002) | 0.005* | 0.008 (− 0.04, 0.055) | 0.751 | 0.53 |
MIG | − 0.01 (− 0.021, 0.001) | 0.079 | − 0.086 (− 0.171, − 0.002) | 0.046 | 0.072 | − 0.003 (− 0.011, 0.005) | 0.49 | − 0.038 (− 0.106, 0.03) | 0.275 | 0.293 |
IL-4 | − 0.014 (− 0.031, 0.002) | 0.085 | − 0.118 (− 0.239, 0.003) | 0.056 | 0.081 | − 0.007 (− 0.019, 0.004) | 0.201 | − 0.08 (− 0.173, 0.013) | 0.092 | 0.104 |
IL-8 | 0.006 (− 0.02, 0.031) | 0.657 | 0.052 (− 0.073, 0.177) | 0.413 | 0.595 | − 0.016 (− 0.034, 0.003) | 0.091 | − 0.019 (− 0.118, 0.081) | 0.712 | 0.644 |