Analytes | Coefficient (CI) | p-value | p-value BH | Coefficient (CI) adjusted | p-value adjusted* | p-value BH adjusted* |
---|---|---|---|---|---|---|
Infected | ||||||
 IL-1β | − 1.248 (− 1.463, − 1.034) | < 0.001 | < 0.001 | − 1.311 (− 1.543, − 1.079) | < 0.001 | < 0.001 |
 IL-1RA | − 0.638 (− 0.743, − 0.534) | < 0.001 | < 0.001 | − 0.67 (− 0.781, − 0.559) | < 0.001 | < 0.001 |
 TNF | − 0.666 (− 0.842, − 0.49) | < 0.001 | < 0.001 | − 0.678 (− 0.867, − 0.489) | < 0.001 | < 0.001 |
 IL-6 | − 1.945 (− 2.144, − 1.746) | < 0.001 | < 0.001 | − 2.023 (− 2.239, − 1.807) | < 0.001 | < 0.001 |
 IFN-α | − 0.025 (− 0.093, 0.043) | 0.470 | 0.486 | − 0.026 (− 0.097, 0.046) | 0.481 | 0.505 |
 IFN-γ | − 0.036 (− 0.099, 0.028) | 0.268 | 0.321 | − 0.039 (− 0.103, 0.026) | 0.235 | 0.293 |
 IL-12 | − 0.035 (− 0.096, 0.027) | 0.265 | 0.321 | − 0.029 (− 0.092, 0.033) | 0.358 | 0.410 |
 IL-17 | − 0.147 (− 0.288, − 0.006) | 0.041 | 0.057 | − 0.149 (− 0.295, − 0.002) | 0.047 | 0.064 |
 IL-10 | − 0.227 (− 0.391, − 0.063) | 0.007 | 0.010 | − 0.235 (− 0.407, − 0.063) | 0.008 | 0.012 |
 IL-13 | − 0.119 (− 0.22, − 0.017) | 0.022 | 0.031 | − 0.149 (− 0.252, − 0.046) | 0.005 | 0.009 |
 IL-4 | − 0.076 (− 0.193, 0.042) | 0.205 | 0.267 | − 0.073 (− 0.196, 0.051) | 0.245 | 0.295 |
 IL-5 | − 0.018 (− 0.167, 0.132) | 0.815 | 0.815 | − 0.033 (− 0.187, 0.121) | 0.673 | 0.673 |
 IL-2 | − 0.064 (− 0.181, 0.052) | 0.278 | 0.321 | − 0.056 (− 0.177, 0.066) | 0.369 | 0.410 |
 IL-2R | − 0.126 (− 0.21, − 0.042) | 0.003 | 0.006 | − 0.123 (− 0.202, − 0.043) | 0.003 | 0.005 |
 IL-15 | − 0.182 (− 0.302, − 0.063) | 0.003 | 0.006 | − 0.168 (− 0.294, − 0.043) | 0.009 | 0.013 |
 IL-7 | − 0.819 (− 1.228, − 0.411) | < 0.001 | < 0.001 | − 0.858 (− 1.279, − 0.436) | < 0.001 | < 0.001 |
 Eotaxin | − 0.043 (− 0.145, 0.058) | 0.401 | 0.430 | − 0.066 (− 0.173, 0.04) | 0.221 | 0.288 |
 IL-8 | − 1.769 (− 1.956, − 1.582) | < 0.001 | < 0.001 | − 1.868 (− 2.067, − 1.669) | < 0.001 | < 0.001 |
 IP-10 | − 0.242 (− 0.369, − 0.116) | < 0.001 | 0.001 | − 0.227 (− 0.36, − 0.094) | 0.001 | 0.002 |
 MCP1 | − 0.29 (− 0.384, − 0.196) | < 0.001 | < 0.001 | − 0.284 (− 0.385, − 0.182) | < 0.001 | < 0.001 |
 MIG | − 0.061 (− 0.181, 0.059) | 0.313 | 0.348 | − 0.044 (− 0.169, 0.081) | 0.488 | 0.505 |
 MIP-1α | − 1.14 (− 1.335, − 0.946) | < 0.001 | < 0.001 | − 1.2 (− 1.41, − 0.991) | < 0.001 | < 0.001 |
 MIP-1β | − 1.413 (− 1.565, − 1.26) | < 0.001 | < 0.001 | − 1.454 (− 1.622, − 1.287) | < 0.001 | < 0.001 |
 RANTES | 0.143 (0.056, 0.23) | 0.001 | 0.003 | 0.109 (0.018, 0.201) | 0.019 | 0.027 |
 EGF | − 0.61 (− 0.778, − 0.442) | < 0.001 | < 0.001 | − 0.684 (− 0.858, − 0.511) | < 0.001 | < 0.001 |
 FGF | − 0.754 (− 1.04, − 0.467) | < 0.001 | < 0.001 | − 0.935 (− 1.222, − 0.648) | < 0.001 | < 0.001 |
 G-CSF | − 0.1 (− 0.169, − 0.032) | 0.004 | 0.006 | − 0.096 (− 0.167, − 0.026) | 0.008 | 0.012 |
 GM-CSF | − 0.291 (− 0.462, − 0.12) | 0.001 | 0.002 | − 0.345 (− 0.524, − 0.167) | < 0.001 | < 0.001 |
 HGF | − 0.16 (− 0.268, − 0.053) | 0.004 | 0.006 | − 0.154 (− 0.261, − 0.046) | 0.005 | 0.009 |
 VEGF | − 0.913 (− 1.057, − 0.769) | < 0.001 | < 0.001 | − 0.967 (− 1.118, − 0.816) | < 0.001 | < 0.001 |
Uninfected | ||||||
 IL-1β | − 2.586 (− 2.949, − 2.223) | < 0.001 | < 0.001 | − 2.551 (− 2.961, − 2.14) | < 0.001 | < 0.001 |
 IL-1RA | − 0.501 (− 0.597, − 0.406) | < 0.001 | < 0.001 | − 0.523 (− 0.628, − 0.418) | < 0.001 | < 0.001 |
 TNF | − 0.684 (− 0.877, − 0.49) | < 0.001 | < 0.001 | − 0.699 (− 0.917, − 0.48) | < 0.001 | < 0.001 |
 IL-6 | − 2.876 (− 3.129, − 2.623) | < 0.001 | < 0.001 | − 2.878 (− 3.162, − 2.595) | < 0.001 | < 0.001 |
 IFN-α | − 0.291 (− 0.344, − 0.239) | < 0.001 | < 0.001 | − 0.288 (− 0.347, − 0.23) | < 0.001 | < 0.001 |
 IFN-γ | 0.002 (− 0.076, 0.08) | 0.960 | 0.960 | − 0.001 (− 0.087, 0.085) | 0.975 | 0.975 |
 IL-12 | − 0.129 (− 0.19, − 0.068) | < 0.001 | < 0.001 | − 0.158 (− 0.217, − 0.098) | < 0.001 | < 0.001 |
 IL-17 | 0.072 (− 0.085, 0.228) | 0.369 | 0.410 | 0.054 (− 0.121, 0.229) | 0.544 | 0.628 |
 IL-10 | − 0.391 (− 0.53, − 0.251) | < 0.001 | < 0.001 | − 0.376 (− 0.532, − 0.221) | < 0.001 | < 0.001 |
 IL-13 | − 0.264 (− 0.404, − 0.123) | < 0.001 | < 0.001 | − 0.272 (− 0.432, − 0.112) | 0.001 | 0.001 |
 IL-4 | − 0.245 (− 0.342, − 0.148) | < 0.001 | < 0.001 | − 0.233 (− 0.34, − 0.125) | < 0.001 | < 0.001 |
 IL-5 | 0.046 (− 0.086, 0.178) | 0.493 | 0.510 | 0.066 (− 0.083, 0.215) | 0.386 | 0.464 |
 IL-2 | 0.076 (− 0.13, 0.282) | 0.467 | 0.501 | 0.012 (− 0.201, 0.224) | 0.914 | 0.946 |
 IL-2R | − 0.12 (− 0.247, 0.007) | 0.064 | 0.087 | − 0.195 (− 0.319, − 0.072) | 0.002 | 0.003 |
 IL-15 | − 0.22 (− 0.546, 0.106) | 0.184 | 0.224 | − 0.356 (− 0.711, − 0.001) | 0.050 | 0.062 |
 IL-7 | − 0.868 (− 1.188, − 0.549) | < 0.001 | < 0.001 | − 0.917 (− 1.264, − 0.579) | < 0.001 | < 0.001 |
 Eotaxin | − 0.081 (− 0.177, 0.015) | 0.099 | 0.129 | 0.011 (− 0.089, 0.112) | 0.824 | 0.883 |
 IL-8 | − 2.096 (− 2.287, − 1.904) | < 0.001 | < 0.001 | − 2.127 (− 2.339, − 1.916) | < 0.001 | < 0.001 |
 IP-10 | − 0.343 (− 0.436, − 0.25) | < 0.001 | < 0.001 | − 0.337 (− 0.441, − 0.233) | < 0.001 | < 0.001 |
 MCP1 | − 0.527 (− 0.615, − 0.44) | < 0.001 | < 0.001 | − 0.515 (− 0.614, − 0.416) | < 0.001 | < 0.001 |
 MIG | − 0.076 (− 0.215, 0.062) | 0.279 | 0.322 | − 0.033 (− 0.186, 0.12) | 0.673 | 0.748 |
 MIP-1α | − 1.267 (− 1.442, − 1.093) | < 0.001 | < 0.001 | − 1.299 (− 1.497, − 1.101) | < 0.001 | < 0.001 |
 MIP-1β | − 1.484 (− 1.629, − 1.349 | < 0.001 | < 0.001 | − 1.478 (− 1.638, − 1.319) | < 0.001 | < 0.001 |
 RANTES | 0.129 (0.05, 0.209) | 0.002 | 0.002 | 0.164 (0.087, 0.241) | < 0.001 | < 0.001 |
 EGF | − 1.555 (− 1.855, − 1.255) | < 0.001 | < 0.001 | − 1.682 (− 2.004, − 1.359) | < 0.001 | < 0.001 |
 FGF | − 0.201 (− 0.499, 0.098) | 0.187 | 0.224 | − 0.336 (− 0.662,− 0.011) | 0.043 | 0.056 |
 G-CSF | − 0.211 (− 0.307, − 0.114) | < 0.001 | < 0.001 | − 0.236 (− 0.341, − 0.131) | < 0.001 | < 0.001 |
 GM-CSF | − 0.195 (− 0.354, − 0.036) | 0.017 | 0.024 | − 0.195 (0.374, − 0.016) | 0.033 | 0.045 |
 HGF | − 0.29 (− 0.364, − 0.215) | < 0.001 | < 0.001 | − 0.305 (− 0.386, − 0.225) | < 0.001 | < 0.001 |
 VEGF | − 1.887 (− 2.159, − 1.614) | < 0.001 | < 0.001 | − 1.938 (− 2.235, − 1.641) | < 0.001 | < 0.001 |