Usefulness of combined screening methods for rapid detection of falsified and/or substandard medicines in the absence of a confirmatory method

Opuni, Kwabena Frimpong-Manso; Nettey, Henry; Larbi, Marvin Adjei; Amartey, Salome Naa Amerley; Nti, Gifty; Dzidonu, Abraham; Owusu-Danso, Patrick; Owusu, Nicholas Amoah; Nyarko, Alexander Kwadwo

doi:10.1186/s12936-019-3045-y

Table 1 Profile of drug samples

From: Usefulness of combined screening methods for rapid detection of falsified and/or substandard medicines in the absence of a confirmatory method

Brand name	Manufacturer	Drug code	Batch	Man. date	Expiry date	Label claim
Artefan	Ajanta, India	AT	1	Jun-17	May-19	Artemether 20 mg/lumefantrine 120 mg
			2	Jun-17	May-19	Artemether 20 mg/lumefantrine 120 mg
			3	Jun-17	May-19	Artemether 20 mg/lumefantrine 120 mg
Coartem Green Leaf	Novartis, Switzerland	CG	1	Sep-17	Aug-19	Artemether 20 mg/lumefantrine 120 mg
			2	Apr-17	Mar-19	Artemether 20 mg/lumefantrine 120 mg
			3	Sep-17	Aug-19	Artemether 20 mg/lumefantrine 120 mg
Coartem Dispersible	Novartis, Switzerland	CD	1	Apr-17	Mar-19	Artemether 20 mg/lumefantrine 120 mg
			2	Dec-16	Nov-18	Artemether 20 mg/lumefantrine 120 mg
			3	May-17	Apr-19	Artemether 20 mg/lumefantrine 120 mg
Combiart	Strides Shasun, India	CO	1	May-16	Apr-18	Artemether 20 mg/lumefantrine 120 mg
			2	May-17	Apr-19	Artemether 20 mg/lumefantrine 120 mg
			3	May-17	Apr-19	Artemether 20 mg/lumefantrine 120 mg
Lonart Forte	Bliss GVS, India	LO	1	Feb-17	Jan-19	Artemether 40 mg/lumefantrine 240 mg
			2	Feb-17	Jan-19	Artemether 40 mg/lumefantrine 240 mg
			3	Sep-16	Aug-18	Artemether 40 mg/lumefantrine 240 mg
Danamether	Danadams, Ghana	DA	1	Sep-17	Sep-19	Artemether 20 mg/lumefantrine 120 mg
			2	Nov-17	Nov-19	Artemether 20 mg/lumefantrine 120 mg
			3	Sep-17	Sep-19	Artemether 20 mg/lumefantrine 120 mg
Gen-M	Genix pharma, Pakistan	GM	1	Nov-16	Nov-18	Artemether 20 mg/lumefantrine 120 mg
Gen-M	Genix pharma, Pakistan	GM	2	May-17	May-19	Artemether 20 mg/lumefantrine 120 mg
Coartem	Novartis, USA	CV^a	1	Jun-14	May-17	Artemether 20 mg/lumefantrine 120 mg
Coartem	Novartis, USA	CW^a	1	Jan-13	Nov-15	Artemether 20 mg/lumefantrine 120 mg
Coartem	Novartis Saglik, Turkey	CX^a	1	Aug-15	Jul-17	Artemether 20 mg/lumefantrine 120 mg
Coartem	Novartis, USA	CY^a	1	Jan-12	Jan-16	Artemether 20 mg/lumefantrine 120 mg
Coartem	Novartis Saglik, Turkey	CZ^a	1	Jun-15	May-17	Artemether 20 mg/lumefantrine 120 mg

^aThese samples were obtained from CDC and had previously confirmed to be of good quality, falsified or substandard

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ISSN: 1475-2875

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