Fig. 3
From: Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages
Mosquito bite challenge. Challenge by bites from 1 or 3 infectious mosquitoes does not guarantee successful infection, while bites from 4 or greater mosquitoes do guarantee successful infection. Filled circle indicates mice that were IVIS positive and positive for blood stage infection; open circle indicates mice that were negative for both IVIS imaging and blood stage infection; filled star indicates mice that were negative for IVIS imaging, but positive for blood stage infection. Dashed lines represent background bioluminescence levels obtained from uninfected mice injected with luciferin