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Fig. 3 | Malaria Journal

Fig. 3

From: In vitro anti-malarial efficacy of chalcones: cytotoxicity profile, mechanism of action and their effect on erythrocytes

Fig. 3

In vitro anti-malarial activity of chalcones on P. falciparum. a Unsynchronized culture of P. falciparum containing different stages of their life cycle; merozoites, early trophozoites (early ring stage), late trophozoites (late ring stage), schizonts, invading merozoites observed from Giemsa-stained slide under 1000× magnification. b Synchronized culture containing only ring stages of P. falciparum after treatment with 5% D-sorbitol observed from Giemsa-stained slide under 1000X magnification. c Dose–response curves (y-axis represents; % parasite matured into schizonts and x-axis represents; log10 concentration) of chloroquine sensitive P. falciparum strain (MRC-2) to different concentration of chalcones number 1,2, 3, 4, 5, 6, 7, 8, 9 and 10 and chloroquine (CHL). d Dose–response curves (y-axis represents; % parasite matured into schizonts and x-axis represents; log10 Concentration) of chloroquine resistant P. falciparum strain (RKL-9) to different concentration of chalcones number 1, 2, 3, 4, 5, 6, 7, 8, 9 and 10, quinine hydrochloride (QNN) and artemisinin (ART)

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