Fig. 6

Microscopic observations of H&E staining on day 5 post P. berghei infection in the spleen of an uninfected control mouse and P. berghei infected mice following the modulation of IL-35. Uninfected mouse spleen showed distinct regions of red (RP) and white (WP) pulp. Note the presence of splenic infarction (yellow arrows) and loss of central germinal structure (red star). Images were acquired at ×40 total magnification (scale bar; 500 µm Photomicrographs are representative images from three experiments