Fig. 7

Microscopic observations of H&E staining on day 5 post P. berghei infection in the brain of an uninfected control mouse and P. berghei infected mice following the modulation of IL-35. Note the presence of intravascular lymphocytes (1), PRBC sequestration and formation of rosettes (2), perivascular haemorrhage (3), perivascular space enlargement (4), lymphocytes (5), pyknotic neurons (6) and pericytes (7). Images were acquired at ×400 total magnification (Scale bar; 50 µm). Photomicrographs are representative images from three experiments