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Table 6 Performance characteristics of the two malaria rapid diagnostic tests by production lot, Magaria, Niger, 2017–2018

From: Clinical diagnostic evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria in an area receiving seasonal malaria chemoprevention in Niger

 TestHigh seasonLow season
Lot numberNaValue95% CINaValue95% CI
SensitivitypLDH24699.297.0–99.915591.085.3–95.0
MN16C6112999.295.7–1005687.575.9–94.8
MN16E6111799.195.2–1004889.677.3–96.5
MN16G625196.186.5–99.5
HRP224699.297.1–99.915585.879.3–90.9
05CDB181A22699.196.8–99.9
05CDB101A6984.173.3–91.8
05CDB232A8687.278.3–93.4
SpecificitypLDH29358.052.1–63.8125292.691.1–94.0
MN16C6113157.448.4–66.035394.691.7–96.7
MN16E6116258.550.4–66.244291.488.4–93.8
MN16G6245792.389.5–94.6
HRP229357.451.5–63.1125293.591.9–94.8
05CDB181A26956.250.0–62.2
05CDB101A48793.090.4–95.1
05CDB232A76593.791.8–95.3
  1. Production lots 05CDB078A (24 participants) and 05FDC006A (20 participants) of the HRP2 RDT were also used during the high season, but given the small number of tests, lot-specific characteristics are not reported here. This explains the slight differences between the overall and lot-specific performance of the HRP2 tests in the high season
  2. aFor sensitivity, N represents all true positives; for specificity, N represents all true negatives tested with a given production lot