Table 6 Performance characteristics of the two malaria rapid diagnostic tests by production lot, Magaria, Niger, 2017–2018
Test | High season | Low season | |||||
|---|---|---|---|---|---|---|---|
Lot number | Na | Value | 95% CI | Na | Value | 95% CI | |
Sensitivity | pLDH | 246 | 99.2 | 97.0–99.9 | 155 | 91.0 | 85.3–95.0 |
MN16C61 | 129 | 99.2 | 95.7–100 | 56 | 87.5 | 75.9–94.8 | |
MN16E61 | 117 | 99.1 | 95.2–100 | 48 | 89.6 | 77.3–96.5 | |
MN16G62 | – | – | – | 51 | 96.1 | 86.5–99.5 | |
HRP2 | 246 | 99.2 | 97.1–99.9 | 155 | 85.8 | 79.3–90.9 | |
05CDB181A | 226 | 99.1 | 96.8–99.9 | – | – | – | |
05CDB101A | – | – | – | 69 | 84.1 | 73.3–91.8 | |
05CDB232A | – | – | – | 86 | 87.2 | 78.3–93.4 | |
Specificity | pLDH | 293 | 58.0 | 52.1–63.8 | 1252 | 92.6 | 91.1–94.0 |
MN16C61 | 131 | 57.4 | 48.4–66.0 | 353 | 94.6 | 91.7–96.7 | |
MN16E61 | 162 | 58.5 | 50.4–66.2 | 442 | 91.4 | 88.4–93.8 | |
MN16G62 | – | – | – | 457 | 92.3 | 89.5–94.6 | |
HRP2 | 293 | 57.4 | 51.5–63.1 | 1252 | 93.5 | 91.9–94.8 | |
05CDB181A | 269 | 56.2 | 50.0–62.2 | – | – | – | |
05CDB101A | – | – | – | 487 | 93.0 | 90.4–95.1 | |
05CDB232A | – | – | – | 765 | 93.7 | 91.8–95.3 | |