Malaria Journal

Table 7 Performance characteristics of two malaria rapid diagnostic tests by participant age, Magaria, Niger, 2017–2018

From: Clinical diagnostic evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria in an area receiving seasonal malaria chemoprevention in Niger

	Test	High season			Low Season
	Age in months	N^a	Value	95% CI	N^a	Value	95% CI
Sensitivity	pLDH	246	99.2	97.0–99.9	155	91.0	85.3–95.0
	3–11	45	100	92.1–100	34	91.2	76.3–98.1
	12–23	58	100	93.7–100	53	86.8	74.7–94.5
	24–35	79	97.4	90.8–99.7	39	92.3	79.1–98.4
	≥ 36	64	100	94.2–100	29	96.6	82.2–99.9
	HRP2	246	99.2	97.1–99.9	155	85.8	79.3–90.9
	3–11	45	100	92.1–100	34	85.3	68.9–95.0
	12–23	58	100	93.8–100	53	81.1	68.0–90.6
	24–35	79	97.5	91.2–99.7	39	89.7	75.8–97.1
	≥ 36	64	100	94.4–100	29	89.7	72.6–97.8
Specificity	pLDH	293	58.0	52.1–63.8	1252	92.6	91.1–94.0
	3–11	103	73.3	63.5–81.6	523	96.2	94.2–97.6
	12–23	108	53.3	43.4–63.0	473	92.0	89.1–94.3
	24–35	50	41.7	27.6–56.8	166	87.9	81.9–92.4
	≥ 36	32	50.0	31.9–68.1	90	84.4	75.3–91.2
	HRP2	293	57.4	51.5–63.1	1252	93.5	91.9–94.8
	3–11	103	73.8	64.2–82.0	523	96.6	94.6–97.9
	12–23	108	52.3	42.5–62.1	473	93.0	90.3–95.1
	24–35	50	38.8	25.2–53.8	166	89.2	83.4–93.4
	≥ 36	32	50.0	31.9–68.1	90	85.6	76.6–92.1

^aFor sensitivity, N represents all true positives; for specificity, N represents all true negatives tested with a given test lot

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