Table 2 Numbers of individuals needed to be treated with an 8-aminoquinoline to prevent one P. vivax infection, assuming 99% P. vivax radical cure rate adjusted for correlation among qPCR test result from same individual
Plasmodium parasites detected in the preceding survey | Number of no subsequent P. vivax infection, n/N | Probability of no subsequent P. vivax infection (95% CI) | Probability no subsequent P. vivax with radical cure assumed | RD (95% CI) with 99% P. vivax radical cure | NNT (95% CI) |
|---|---|---|---|---|---|
P. falciparum (monoinfection) | 487/534 | 0.090 (0.068, 0.119) | 0.99 | 0.080 (0.045, 0.116) | 12 (9, 22) |
P. falciparum + P. vivax (mixed infection) | 113/217 | 0.466 (0.402, 0.540) | 0.99 | 0.456 (0.359, 0.553) | 2 (2, 3) |
P. vivax (monoinfection) | 585/1169 | 0.447 (0.416, 0.480) | 0.99 | 0.437 (0.392, 0.482) | 2 (2, 3) |
Negative | 14,524/15,039 | 0.036 (0.033, 0.039) | 0.99 | 0.026 (0.022, 0.031) | 38 (33, 46) |