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Table 5 Mean geometric IC50 values for each component of AL and ASAQ at D0 (before treatment) versus day of treatment failure among treatment participants

From: In vivo/ex vivo efficacy of artemether–lumefantrine and artesunate–amodiaquine as first-line treatment for uncomplicated falciparum malaria in children: an open label randomized controlled trial in Burkina Faso

TreatmentnnP value
IC50 at D0 in nM (IC 95%)IC50 at DoR in nM (IC 95%) 
19.80 (17.83–21.99)24.94 (20.68–30.08)0.94
0.85 (0.76–0.95)0.66 (0.47–0.93)0.96
0.8 (0.72–0.90)0.67 (0.54–0.83)0.43
24.13 (20.45–28.46)37.07 (28.37–48.44)0.05
  1. nM nanomolar, DoR day of recurrent parasitaemia, ASAQ amodiaqine–artesunate, AL artemether lumefantrine, MDA monodesethylamodiaquine, DHA dihydroartermisinin, LUM lumefantrine