|
Authors
|
Countries
|
Number of P. falciparum samples positive with reference method but negative with PfHRP-based RDTa
|
Number of isolates with deletions in pfhrp2 gene (%)
|
Number of isolates with deletions in pfhrp3 gene (%)
|
|---|
|
Koita et al. [26]b
|
Mali
|
22
|
10 (45.5%)
|
NA
|
|
Wurtz et al. [27]b
|
Senegal
|
7
|
3 (42.9%)
|
6 (85.8%)
|
|
Amoah et al. [28]
|
Ghana
|
38
|
6 (15.8%)
|
NA
|
|
Beshir et al. [29]
|
Kenya
|
NA
|
NA
|
NA
|
|
Gupta et al. [30]
|
Mozambique
|
69
|
1 (1.4%)
|
0 (0.0%)
|
|
Kozycki et al. [31]
|
Rwanda
|
140
|
32 (22.9%)
|
NA
|
|
Menegon et al. [32]
|
Eritrea
|
NA
|
NA
|
NA
|
|
Parr et al. [33]
|
Democratic Republic of the Congo
|
783
|
149 (19.0%)
|
NA
|
|
Berhane et al. [35]
|
Eritrea
|
31
|
31 (100%)
|
NA
|
|
Nderu et al. [36]b
|
Kenya
|
2
|
0 (0%)
|
0 (0%)
|
|
Ranadive et al. [34]b
|
Swaziland
|
9
|
0 (0%)
|
0 (0%)
|
|
Funwei et al. [38]
|
Nigeria
|
31
|
7 (22.6%)
|
NA
|
|
Kobayashi et al. [39]
|
Zambia
|
36
|
3 (8.3%)
|
NA
|
|
Kumar et al. [42]b
|
India
|
2
|
2 (100%)
|
2 (100%)
|
|
Bharti et al. [43]
|
India
|
50
|
36 (72.0%)
|
27 (54.0%)
|
|
Pati et al. [44]
|
India
|
58
|
38 (65.5%)
|
24 (41.38%)
|
- PfHRP: Plasmodium falciparum histidine-rich protein; NA: not applicable; PCR: polymerase chain reaction; pLDH: lactate dehydrogenase; RDT: rapid diagnostic test
- aReference method was microscopy, PCR or pLDH RDT
- bThese studies were excluded from the meta-analysis of percentage of false negative samples in which deletions in pfhrp2/3 genes were found due to small sample size
