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Table 3 Measures of DNA sequence polymorphisms at the HABP 36727 of RH5 among Nigerian P. falciparum populations (N = 195)

From: Genetic polymorphisms in malaria vaccine candidate Plasmodium falciparum reticulocyte-binding protein homologue-5 among populations in Lagos, Nigeria

Study areas (n = 195)

Segregating sites (S)

Singleton variable sites

Parsimony informative sites

Total no of mutation

K

H

Hd ± S.D

Π ± S.D

dN/dS ± S.E

Tajima’s D

Ijede (n = 54)

13

13

0

13

5.20

3

0.403 ± 0.024

0.0064 ± 0.0058

0.017 ± 0.005

− 1.210

Lekki (n = 63)

11

11

0

11

7.53

2

0.671 ± 0.314

0.0091 ± 0.0012

0.013 ± 0.313

− 0.837

Ajeromi (n = 78)

9

8

1

10

7.33

2

0.509 ± 0.027

0.0080 ± 0.0070

0.009 ± 0.015

− 0.843

Total (n = 195)

15

6

9

15

3.727

3

0.318 ± 0.016

0.0046 ± 0.0001

0.011 ± 0.020

− 1.717

  1. S number of segregating (polymorphic/variable) sites, K average number of pairwise nucleotide differences, H number of haplotypes, Hd Haplotype diversity, π observed average pairwise nucleotide diversity, dN/dS rate of non-synonymous mutations minus rate of synonymous mutations, D Tajima’s D test statistics
  2. S.E was used in place of SD to correct for extraneous values of dN/dS