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Table 6 Prediction of AsAPN-1 and AgAPN-1 presented peptides by common MHC-II alleles in Iran using NetMHCII

From: Identification, molecular characterization and expression of aminopeptidase N-1 (APN-1) from Anopheles stephensi in SF9 cell line as a candidate molecule for developing a vaccine that interrupt malaria transmission

AgAPN-1

 MHC Alleles

MHC DP Allele

MHC DQ Allele

MHC DR Allele

Number of peptides

 Binding situation

High binders 0

Weak binders 10

High binders 0

Weak binders 35

High binders 94

Weak binders 226

687

 Highest affinity (nM)

207.9

54.7

4.3

 

AsAPN-1

 MHC alleles

MHC DP Allele

MHC DQ Allele

MHC DR Allele

Number of peptides

 Binding situation

High binders 58

Weak binders 166

High binders 19

Weak binders 145

High binders 290

Weak binders 423

1011

 Highest affinity (nM)

5.1

20.5

4.2

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