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Table 3 Multivariate analysis of specific IgG, IgG1 and IgG3 antibody response levels in children

From: Pattern of antibody responses to Plasmodium falciparum antigens in individuals differentially exposed to Anopheles bites

Ab responseCovariate factorsTotal populationPetessouDar-es-Salam
EstimatepEstimatepEstimatep
IgG anti-PfMSP1Constant1.240 1.488 0.172 
Age0.0180.580.0690.715− 0.0050.871
Group of exposure (ref = low exposure)− 0.4430.043− 1.020.0030.2680.232
Site (ref = Petessou)− 0.823< 0.001    
IgG1 anti-PfMSP1Constant1.230 1.623 0.245 
Age0.0060.883− 0.0040.943− 0.0120.753
Group of exposure (ref = low exposure)− 0.3970.107− 1.090.0060.3860.148
Site (ref = Petessou)− 0.660.008
IgG3 anti-PfMSP1Constant0.951 0.881 0.081 
Age0.0570.0660.0810.1540.0270.363
Group of exposure (ref = low exposure)− 0.4220.033− 0.6530.047− 0.1260.496
Site (ref = Petessou)− 0.895< 0.0001
Ab responseCovariate factorsTotal populationPetessouDar-es-Salam
EstimatepEstimatepEstimatep
IgG anti-PfAMA1Constant− 0.025 1.64 0.129 
Age0.0180.5620.0440.416− 0.0070.813
Group of exposure (ref = low exposure)0.1960.3240.2220.5060.2110.311
Site (ref = Petessou)− 1.871< 0.0001
IgG1 anti-PfAMA1Constant0.028 2.37 0.216 
Age0.0060.870.0290.683− 0.0080.813
Group of exposure (ref = low exposure)0.3790.1250.5570.2010.2160.366
Site (ref = Petessou)− 2.576< 0.0001
IgG3 anti-PfAMA1Constant0.021 1.42 0.045 
Age0.0460.1670.0690.2620.0140.548
Group of exposure (ref = low exposure)− 0.2790.198− 0.5250.1740.0530.724
Site (ref = Petessou)− 1.462< 0.0001