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Table 1 The pfdhfr/pfdhps haplotypes and pfgch1 copy number variation of P. falciparum separated by Thailand-neighboring countries between 2008 and 2016

From: Molecular characterization of Plasmodium falciparum antifolate resistance markers in Thailand between 2008 and 2016

AreaYearaDHFRDHPSGCH1Num.
A16VC50RN51IC59RS108NI164LA/S436FA437GK540E/NA581GA613S/TSingle/Multiple
Thailand-Myanmar border2008–2010ACNRNLA/SGEAAS3
ACNRNLA/SGEGAS1
ACIRNIA/SGEAAM1
ACIRNLA/SGEAAS4
ACIRNLA/SGEAAM6
ACIRNLA/SGEGAS12
ACIRNLA/SGEGAM6
ACIRNLFGEATS2
2011–2013ACNRNIA/SGEGAM1
ACNRNLA/SGEGAS1
ACIRNIA/SGEAAS1
ACIRNIA/SGEAAM1
ACIRNIA/SGEGAS1
ACIRNIA/SGEGAM5
ACIRNIA/SGKAAS2
ACIRNLA/SGEAAS11
ACIRNLA/SGEAAM4
ACIRNLA/SGEGAS19
ACIRNLA/SGEGAM17
ACIRNLA/SGNGAM1
ACIRNLFGEATS1
ACIRNLFGEATM1
ACIRNLFGEGAS1
ACIRNLFGEGAM5
2014–2016ACIRNIA/SGEAAS2
ACIRNIA/SGEAAM1
ACIRNIA/SGKAAS2
ACIRNLA/SGEAAS4
ACIRNLA/SGEAAM12
ACIRNLA/SGEGAS5
ACIRNLA/SGEGAM10
Total146
Thailand–Cambodia border2008–2010ACIRNIA/SGEAAS1
ACIRNIA/SGNGAS2
ACIRNLA/SGEAAS2
ACIRNLA/SGEAAM1
ACIRNLA/SGNGAS6
2014–2016ACIRNIA/SGEAAS5
ACIRNIA/SGKAAS1
ACIRNIA/SGKAAM1
ACIRNLA/SGEAAS1
ACIRNLA/SGNGAS19
ACIRNLA/SGNGAM1
Total40
Thailand–Malaysia border2008–2010ACIRNIA/SGKAAS2
ACIRNLA/SGKAAS1
2011–2013ACIRNIA/SGKAAS7
2014–2016ACIRNIA/SGKAAS13
ACIRNIA/SGKGAM5
ACIRNIA/SGKGAS19
Total47
  1. Each italic upper script letters represent mutation observed in the amino acid at the corresponding position
  2. aThe mutations observed are grouped based on year of sample collection