TY - JOUR AU - Raghunandan, Rama AU - Mayer, Bryan T. AU - Flores-Garcia, Yevel AU - Gerber, Monica W. AU - Gottardo, Raphael AU - Jhun, Hugo AU - Herrera, Sonia M. AU - Perez-Ramos, Daniel W. AU - Locke, Emily AU - King, C. Richter AU - Zavala, Fidel PY - 2020 DA - 2020/03/17 TI - Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein JO - Malaria Journal SP - 113 VL - 19 IS - 1 AB - New strategies are needed to reduce the incidence of malaria, and promising approaches include the development of vaccines and monoclonal antibodies (mAbs) that target the circumsporozoite protein (CSP). To select the best candidates and speed development, it is essential to standardize preclinical assays to measure the potency of such interventions in animal models. SN - 1475-2875 UR - https://doi.org/10.1186/s12936-020-03181-0 DO - 10.1186/s12936-020-03181-0 ID - Raghunandan2020 ER -