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Fig. 3 | Malaria Journal

Fig. 3

From: Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein

Fig. 3

Administered dose versus circulating serum antibodies in reduction in parasite liver burden assay (a) and from protection from parasitaemia assay (b): serum samples from an hour pre-challenge blood draw from all mice that received AB311 or AB317 were analysed (n = 5 in all groups). In anti-CSP ELISA and the circulating serum antibody levels measured in µg and plotted against the administered dose. The mid-line of the box denotes the median and the ends of the box denote the 25th and 75th percentiles. The whiskers denote the most extreme data points that are no more than 1.5 times the interquartile range (i.e., height of the box). Study numbers shown are consistent with Tables 2 and 3

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