Malaria Journal

Table 3 Comparison of infection frequency in three protection from parasitaemia studies

From: Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein

mAb	Dose	Study 1		Study 2		Study 3
mAb	Dose	Infected	Protection (%)	Infected	Protection (%)	Infected	Protection (%)
311	100	7/7	0	7/7	0	7/7	0
	300	5/7	29	4/7	43	4/7	43
	600	0/7	100	0/7	100	0/7	100
317	100	6/7	24	7/7	0	7/7	0
	300	2/7	61	0/7	100	3/7	57
	600	0/7	100	0/7	100	0/7	100

Mice (N = 7) received either AB311 or AB317 at 100, 300 or 600 µg dose and were challenged with 5 mosquito bites post antibody administration. Appearance of blood parasites were scored from day 4 to 12 and the percent parasite free at day 12 from each group depicted

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ISSN: 1475-2875

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