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Table 3 Comparison of infection frequency in three protection from parasitaemia studies

From: Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein

mAbDoseStudy 1Study 2Study 3
InfectedProtection (%)InfectedProtection (%)InfectedProtection (%)
3111007/707/707/70
3005/7294/7434/743
6000/71000/71000/7100
3171006/7247/707/70
3002/7610/71003/757
6000/71000/71000/7100
  1. Mice (N = 7) received either AB311 or AB317 at 100, 300 or 600 µg dose and were challenged with 5 mosquito bites post antibody administration. Appearance of blood parasites were scored from day 4 to 12 and the percent parasite free at day 12 from each group depicted