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Table 6 Single dose comparison results between AB311 and AB317

From: Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein

DoseStudyProportion infectedBarnard P valueLog Rank P value
AB311AB317
100 µgStudy 11.000.860.2600.002
Study 21.001.001.0000.096
Study 31.001.001.0000.043
Pooled1.000.950.263< 0.001
300 µgStudy 10.710.290.0900.033
Study 20.570.000.0120.035
Study 30.570.430.3950.153
Pooled0.620.240.0070.002
  1. The proportion infected at each dose were compared using the Barnard test and survival times (Fig. 4) were compared using the log-rank test using the exact conditional distribution