Fig. 2

Individual variations of antibody responses to SE (a), MSP1p19 (b) and LSA1₄₁ (c) in individuals from Dielmo and Ndiop between 2002 and 2013. This figure show detailed individual antibody responses in Dielmo and Ndiop as dot plot in 2002 and 2013. Red arrows link responses from each individual from 2002 to 2013 in groups of younger villagers (< 15 years in 2002) and older ones (> 15 years). Arrows linking individual measures that did not decrease between 2002 and 2013 are in black colour. The decrease of antibody levels was significant for all antigens and for all age groups in Dielmo (p < 0.01, Wilcoxon signed rank test for paired data). In Ndiop, there was a significant decrease for IgG to SE and MSP1p19 (p < 0.05) but not LSA1₄₁. The mean decay of Ab levels ranged from 17 to 49%