Table 1 Mutations in Pfk13 previously observed in Africa and in the present study
From: Amplicon deep sequencing of kelch13 in Plasmodium falciparum isolates from Senegal
SNPs | 2015/2016 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
This Study | COG (n/N) | ROC (n/N) | GAB (n/N) | GHA (n/N) | IC (n/N) | KEN (n/N) | MAL (n/N) | SEN (n/N) | UGA (n/N) | SEN (n/N) | UGA (n/N) | |
N141–N142NN | 3/81 | – | – | – | – | – | – | – | – | – | – | – |
N142NN | 5/81 | – | – | – | – | – | – | – | 7/58 | – | – | – |
T149S | 1/81 | – | – | – | – | – | – | – | 1/58 | – | 4/64 | – |
K189N | 15/81 | – | – | – | – | – | – | – | 31/207 | 1/29 | – | – |
K189T | 28/81 | – | – | – | – | – | – | – | 130/207 | 10/29 | 27/64 | – |
T478T | 2/81 | – | – | – | – | 1/98 | 1/108 | – | – | – | – | – |
A578S | 1/81 | 1/82 | 2/127 | 1/93 | 1/234 | – | 3/108 | 1/91 | – | 1/133 | – | – |
V637I | 1/81 | – | – | – | – | – | – | – | – | – | 3/92 | 1/132 |