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Table 1 Mutations in Pfk13 previously observed in Africa and in the present study

From: Amplicon deep sequencing of kelch13 in Plasmodium falciparum isolates from Senegal

SNPs2015/20162013/2014 [7, 20, 23,24,25,26, 29]2012/2013 [29] [33]
This StudyCOG (n/N)ROC (n/N)GAB (n/N)GHA (n/N)IC (n/N)KEN (n/N)MAL (n/N)SEN (n/N)UGA (n/N)SEN (n/N)UGA (n/N)
N141–N142NN3/81
N142NN5/817/58
T149S1/811/584/64
K189N15/8131/2071/29
K189T28/81130/20710/2927/64
T478T2/811/981/108
A578S1/811/822/1271/931/2343/1081/911/133
V637I1/813/921/132
  1. “N” is the number of samples sequenced and “n” is the number of samples containing mutant allele
  2. COG Congo-Kinshasha, ROC Republic of Congo, GAB Gabon, GHA Ghana, IC Côte d’Ivoire, KEN Kenya, MAL Mali, SEN Senegal, UGA Uganda