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Fig. 1 | Malaria Journal

Fig. 1

From: Immunization with virus-like particles conjugated to CIDRα1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies

Fig. 1

Characterization of VLP-antigen conjugated vaccines. a Dynamic light scattering (DLS) showing SpyT-VLP (blue) with an average size of 37 nm (12.18% polydispersity, Pd). After coupling VLP to catCIDRα1.4 (brown) or CIDRα1.4cat (green) the size increases to 56 nm (12.19%Pd) and 88 nm (27.83 %Pd), respectively. b SDS-gel loaded with catCIDRα1.4 or CIDRα1.4cat antigens (32kDa) mixed with SpyT-VLP (16kDa) or naked VLP (8kDa): 1. SpyT-VLP; 2. Naked VLP + catCIDRα1.4; 3. SpyT-VLP + catCIDRα1.4; 4. Naked VLP + CIDRα1.4cat; 5. SpyT-VLP + CIDRα1.4cat

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Malaria Journal

ISSN: 1475-2875

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