Fig. 5

Specificity and reactivity of the sera of rPoMSP4-immunized mice using PoAMA1 and PoMSP1 proteins. The reactivity of sera from mice immunized with rPoMSP4 was evaluated using rPoAMA1 and rPoMSP1 proteins. a, b Cross-reaction of rPoAMA1 proteins with antisera from mice immunized with rPoMSP4. No significant differences were observed between PocMSP4, PocAMA1, or PowAMA1 and the anti-PocMSP4 antisera and between PowMSP4, PocAMA1, or PowAMA1 and the anti-PowMSP4 antisera (p > 0.05). c, d Cross-reaction of rPoMSP1 proteins with antisera from mice immunized with rPoMSP4. Significant differences between groups are indicated on the graph. No significant difference was found between rPocMSP4 and PowMSP1 to anti-rPocMSP4 sera (p = 0.9063) (c) and between rPowMSP4 and PowMSP1 to anti-rPowMSP4 sera (p < 0.0430) (d)