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Table 2 Baseline characteristics by exposure level (no exposure, exposed to ACT, exposed to quinine), ASAP cohort, 2015

From: First trimester use of artemisinin-based combination therapy and the risk of low birth weight and small for gestational age

Characteristic

No anti-malarial use in first trimester

Confirmed ACT use in first trimester

Confirmed quinine use in first trimester

All pregnancies

N (%)

N (%)

N (%)

N (%)

Total

1797 (100)

92 (100)

26 (100)

1915 (100)

Country

 Burkina Faso

603 (33.6)

31 (33.7)

22 (84.6)

656 (34.3)

 Mozambique

643 (35.8)

22 (23.9)

4 (15.4)

669 (34.9)

 Kenya

551 (30.7)

39 (42.4)

0 (0.0)

590 (30.8)

Age at recruitment (years)

 Range

12.4–49.0

15.0–45.0

17.0–36.0

12.4–49.0

 Mean (SD)

25.7 (6.55)

25.6 (6.63)

24.7 (6.04)

25.6 (6.54)

 < 20

394 (21.9)

17 (18.5)

7 (26.9)

418 (21.8)

 20–24

465 (25.9)

30 (32.6)

7 (26.9)

502 (26.2)

 25–29

444 (24.7)

19 (20.7)

7 (26.9)

470 (24.5)

 30+

494 (27.5)

26 (28.3)

5 (19.2)

525 (27.4)

Gravidity

 Primigravida

378 (21.0)

23 (25.0)

8 (30.8)

409 (21.4)

 1–3 pregnancies

943 (52.5)

45 (48.9)

11 (42.3)

999 (52.2)

 4 or more pregnancies

473 (26.3)

24 (26.1)

7 (26.9)

504 (26.3)

 Missing

3 (0.2)

0 (0.0)

0 (0.0)

3 (0.2)

Marital status

 Single

354 (19.7)

20 (21.7)

0 (0.0)

374 (19.5)

 Married or cohabiting

1442 (80.2)

72 (78.3)

26 (100.0)

1540 (80.4)

 Missing

1 (0.1)

0 (0.0)

0 (0.0)

1 (0.1)

Education

 Primary not completed

348 (19.4)

16 (17.4)

0 (0.0)

364 (19.0)

 Primary completed

1176 (65.4)

62 (67.4)

24 (92.3)

1262 (65.9)

 Secondary completed

271 (15.1)

14 (15.2)

2 (7.7)

287 (15.0)

 Missing

2 (0.1)

0 (0.0)

0 (0.0)

2 (0.1)

HIV status

 Negative

1427 (79.4)

70 (76.1)

23 (88.5)

1520 (79.4)

 Positive

279 (15.5)

13 (14.1)

1 (3.8)

293 (15.3)

 Missing

91 (5.1)

9 (9.8)

2 (7.7)

102 (5.3)

Gestational age at recruitment (weeks)

 Mean (SD)

21.3 (7.39)

18.8 (8.72)

16.8 (5.56)

21.2 (7.88)

Gestational age at delivery (weeks)

 Mean (SD)

38.9 (1.80)

39.0 (1.77)

38.8 (1.65)

38.9 (1.79)

  1. SD standard deviation