Table 4 Adjusted associations for low birth weight and small for gestational age
Prevalence-ratio (95% CIc) | ||||
|---|---|---|---|---|
Unadjusteda | p-value | Adjustedb | p-value | |
LBW | ||||
Birth weights measured within 24 h of birth (N) | 1543 | 1533 | ||
No exposure | 1 (reference) | 1 (reference) | ||
Artemisinin | 0.80 (0.31; 1.62) | 0.575 | 0.91 (0.36; 1.81) | 0.809 |
Quinine | 1.95 (0.87; 3.42) | 0.099 | 2.17 (1.00; 3.65) | 0.049 |
Birth weights measured within 7 days of birth (N) | 1915 | 1905 | ||
No exposure | 1 (reference) | 1 (reference) | ||
Artemisinin | 1.08 (0.55; 1.85) | 0.806 | 1.19 (0.61; 2.00) | 0.579 |
Quinine | 1.87 (0.85; 3.27) | 0.109 | 2.13 (0.98; 3.59) | 0.055 |
Quinine vs artemisinin | ||||
Artemisinin | 1 (reference) | 1 (reference) | ||
Quinine with no Kenya data (N = 79) | 2.03 (0.73; 5.86) | 0.172 | 1.70 (0.60; 5.17) | 0.321 |
Quinine with Kenya data (N = 118) | 3.18 (1.02; 11.56) | 0.047 | 1.93 (0.72; 5.68) | 0.188 |
SGA | ||||
Birth weights measured within 24 h of birth (N) | 1520 | 1514 | ||
No exposure | 1 (reference) | 1 (reference) | ||
Artemisinin | 0.76 (0.37; 1.31) | 0.363 | 0.83 (0.41; 1.42) | 0.516 |
Quinine | 1.31 (0.54; 2.43) | 0.495 | 1.19 (0.50; 2.17) | 0.660 |
Birth weights measured within 7 days of birth (N) | 1888 | 1882 | ||
No exposure | 1 (reference) | 1 (reference) | ||
Artemisinin | 0.81 (0.43; 1.31) | 0.417 | 0.78 (0.43; 1.25) | 0.337 |
Quinine | 1.29 (0.55; 2.40) | 0.514 | 1.11 (0.47; 2.02) | 0.789 |
Quinine vs artemisinin | ||||
Artemisinin confirmed | 1 (reference) | 1 (reference) | ||
Quinine confirmed with no Kenya data (N = 78) | 13.75 (2.16; 409.72) | 0.003 | 13.11 (1.82; 441.93) | 0.004 |
Quinine confirmed with Kenya data (N = 116) | 14.44 (2.18; 400.29) | 0.004 | 12.04 (1.84; 330.23) | 0.008 |