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Fig. 4 | Malaria Journal

Fig. 4

From: Comparison of ELISA with electro-chemiluminescence technology for the qualitative and quantitative assessment of serological responses to vaccination

Fig. 4

Testing of closely related antigens to identify antigenic competition. Human CSP-immune serum pool (1:5000 dilution) tested for reactivity against either singleplexed antigens (SP) or multiplexed antigens. a In addition, titrations of CSP C-terminus specific mouse mAb 1E9 b and CSP-repeat-specific mAb 1A6 c were tested reactivity against either singleplexed antigens (SP) or multiplexed antigens. Data are expressed as mean luminescence signal (MLS) of two independent experiments for each panel.  % CV was less than 5% for all tests. The luminescence signal with malaria-naïve serum (specificity control) did not exceed MLS < 1000

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